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How to interpret iron tests: In generally healthy people, serum or plasma ferritin is considered the best way to assess early stages of iron deficiency, before IDA, and it corresponds well with iron tissue stores

Qin Y, Ge G, Yang P, et al

We hypothesize that reduced CPT-I activity may contribute to persistent fatigue in these congenital hypothyroid patients, even after levothyroxine therapy, which alone may be insufficient to fully address the downstream metabolic consequences of TPO and TSHR gene mutations present in this cohort