High blood pressure, atherogenic cholesterol particles, elevated blood sugar, smoking, chronic kidney disease, inflammation, inactivity, poor sleep, and genetic factors may accelerate vascular damage
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In a trial of patients with T2DM and BMI 27 kg/m2 or more receiving semaglutide injection for weight management, retinal disorders were reported by 6.9% of patients treated with semaglutide 2.4 mg/week, 6.2% of patients treated with semaglutide 1 mg/week, and 4.2% of patients treated with placebo
