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Patients with vegan diets, post-bariatric history, or absorption challenges who need consistent repletion

5-Amino-1MQ Also known as: 5-amino-1-methylquinolinium, NNMTi TL;DR Increases intracellular NAD+ levels via NNMT inhibition (preclinical) Reduces body weight and white adipose mass in diet-induced obese mice Improves grip strength by up to 60% in aged mice when combined with exercise Suppresses lipogenesis in adipocytes without affecting food intake Community-Reported Side EffectsAnecdotal

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For patients with pernicious anaemia or severe malabsorption , oral supplementation with either form is usually insufficient