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Subsequently, caspase-1 cleaves GSDMD, releasing the GSDMD-NT fragment, which induces pore formation, cell swelling, and ultimately pyroptosis [82]

477 LiuXet al

To deliver oxygen to the tissues, erythrocytes must be able to dynamically adapt to and compensate for the constantly changing flow conditions along the vascular tree and particularly in the narrowest capillaries to deform significantly without rupturing