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Redox Biol 12:883896 Huang MM, Overstreet DH, Knapp DJ, Angel R, Wills TA, Navarro M, Rivier J, Vale W, Breese GR (2010) Corticotropin-releasing factor (CRF) sensitization of ethanol withdrawal-induced anxiety-like behavior is brain site specific and mediated by CRF-1 receptors: relation to stress-induced sensitization

Included case studies and case series did not indicate long-term, irreversible damage, and symptoms were reported to resolve following treatment or removal of exposure

A large sample size and long-term intervention are required for validation (41)

Mucosal t-cell phenotypes in persistent atopic and nonatopic rhinitis show an association with mast cells