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10.1371/journal.pone.0236450 115

These findings suggest that managing cellular copper levels through metabolic reprogramming is a simple way to switch the main energy metabolism pathway of cells between glycolysis and oxidative phosphorylation (OXPHOS) to control cell fate

Intensive and continuous pericellular claudin-5 staining was observed in the model and the shape of the hECs also indicated a typical brain endothelial cell layer (Fig