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Determination of trimethylamine-N-oxide by a simple isocratic high-throughput liquid-chromatography tandem mass-spectrometry method

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The specific nNOS inhibitor 7-nitroindazole protects against dopaminergic neuron depletion in animals treated with 6OHDA 126 or MPTP 12 , even preventing motor impairments such as apomorphine induced contralateral rotations 127 and catalepsy 12