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Description

Rowat, A

Across diverse cell sources (dental pulp, mesenchyme, olfactory mucosa, induced pluripotent cells, Tregs and even homeostatic M2 microglia) the common therapeutic denominator is delivery of RNA cargo that throttles one of three pressure points in the pyroptotic cascade: (i) inflammasome activation (NLRP3 or AIM2), (ii) execution (GSDMD) or (iii) transcriptional priming (NF-B/NKAP)

Behav Neurosci 120:211216 Pierce K, Haist F, Sedaghat F, Courchesne E (2004) The brain response to personally familiar faces in autism: findings of fusiform activity and beyond