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As such, an effective treatment would be expected to augment striatal synaptic connectivity, protect SN neurons from underlying death inducers, and ideally stimulate the replacement of lost SN neurons from preexisting pools of neural stem cells

This safety profile in animal models provides some reassurance about the compounds fundamental tolerability, though extrapolation to humans requires appropriate caution

Interaction Uncertainty : Potential interactions with medications or underlying conditions remain unknown due to the absence of controlled human studies

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