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acknowledges the funding provided by CONAHCYT in the form of scholarship as member of the National System of Researchers (SNI 1047863) and the financial support of Federico Baur Endowed Chair in Nanotechnology (ILST002-23ID69001)

Part C, Toxicology & Pharmacology, 248 , Article 109083

Results from these multi-scale approaches reveal that cysteines 8 and 83 are the main targets of glutathionylation and oxidation that lead to loss of activity, while cysteine 79 is less vulnerable to oxidation