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Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats

Interestingly, IL-6 exposure reduced the frequency of spontaneous inhibitory postsynaptic currents (sIPSCs), while soluble IL-6 initially decreased sEPSCs, followed by increased sEPSCs and cAMP response element-binding protein (CREB) phosphorylation (138)