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Detection of minimal residual disease in chronic lymphocytic leukemia (CLL) using fluorescence in situ hybridization (FISH) studies of trisomy 12

Additionally, activation of the aryl hydrocarbon receptor (AHR) signaling pathway has been implicated in the transcriptional and possibly epigenetic regulation of both CYP27B1 and CYP24A1 ( 3.2 Dysregulation of vitamin D metabolism in chronic kidney disease In the context of CKD, the regulatory network governing vitamin D metabolism becomes markedly disrupted

no human validation Approach Published mouse regimen Pattern 5 mg/kg IP, ~3x/week Duration Several weeks Notes Animal only

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