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J Trace Elem Med Biol 48:172180

Dec 8 2020;doi:10.2174/1874467213666201209105005 Marx W, McKavanagh D, McCarthy AL, et al

It adds a targeted, potent anti-inflammatory effect specifically for the gut, making this protocol uniquely powerful for addressing gut-related inflammation and its systemic effects

This could primarily be allocated to the pivotal role of insulin in regulating carbohydrate and lipid metabolisms, but also to the involvement of many of these intermediates in bidirectionally modulating insulin production and signaling (e.g., influence of hyperglycemia in the development of IR, lipotoxicity induced by acyl-carnitines and FFAs) [4]