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Hydroxocobalamin is a prescription-only medicine (POM) that should be administered by appropriately trained healthcare professionals, typically following a standard regimen of loading doses (e.g., 1mg on alternate days for 1-2 weeks) followed by maintenance doses (1mg every 2-3 months, or every 2 months if neurological symptoms are present)

These include: Lack of energy Difficulty concentrating Tingling or numbness in the hands or feet Rapid heart rate Loss of appetite and weight loss Nausea and diarrhea Glossitis (tender, swollen tongue) Vitamin B12 deficiency can be detected through blood testing

Any mention of published preclinical data, mechanisms of action, or experimental outcomes is provided exclusively for scientific context and literature review

Neurologic manifestations are caused by progressive demyelination and can include peripheral neuropathy, areflexia, and the loss of proprioception and vibratory sense