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Copper inducing A42 rather than A40 nanoscale oligomer formation is the key process for A neurotoxicity

The lower drying temperature resulted in the solvent not being removed from the solution to be measured, while the higher drying temperature also caused the film on the window sheet to be unformed and cracked, which affected the detection of IR spectra

Based on the finding that Cu chelator exhibit a potent suppression effect on Cu-induced cell death, it would be important to carry out appropriate Cu-deprivation strategies to reduce the level of intracellular Cu 2+ ion in Cu-overload conditions, for example, using a Cu chelator, reducing dietary Cu intake, and/or genetically modifying Cu transporters