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Once ingested, cyanocobalamin needs to be converted to a methylated form of vitamin B12 so the body can actually utilize it

Additionally, they question the utility of the 2 M endpoint as a basis to define a permissible exposure level for Cd and its toxicity threshold level, given that a low eGFR is a pathological sign for the diagnosis of chronic kidney disease (CKD) [2]

That said, high-level or specialized testing (like what might be used in professional sports) could look for substances not included in standard panels