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On the other hand, the JAK/STAT pathway, activated by cytokines such as IL-6 and interferons, contributes to BBB dysfunction by dimerizing STAT proteins upon activation which translocate to the nucleus, where they regulate the expression of genes involved in inflammation, cell survival, and barrier function

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However, rapid or excessive increases in iodine in previously iodine-deficient populations can inadvertently induce hyperthyroidism in some individuals

In mathematics, convex and concave functions describe how curves behave in terms of their curvature