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GSDME as an executioner of chemotherapy-induced cell death

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Furthermore, bacterial pneumonia can induce a systemic inflammatory response that leads to severe outcomes such as sepsis and multi-organ failure ( A favorable prognosis for bacterial pneumonia depends on timely and efficient treatment because of its extremely high incidence and potentially dangerous outcomes ( The challenges mentioned above can be addressed through nanotechnology

The transcription factor central to the production of inflammatory cytokines, NFB, is strongly activated in the alveoli of patients with ARDS 62,63 Unfortunately, mechanical ventilation, the primary modality for treating ARDS, itself exacerbates oxidative stress