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Separately, ROS-mediated activation of c-JUN also accelerated wound healing in diabetic rats through increases in angiogenesis and re-epithelialisation 123 , whilst NOX-produced H 2 O 2 -activation of the JNK pathway increased epithelial cell proliferation in adult zebrafish tailfin healing 19

Important Safety Reminders Medical Supervision Required: AOD-9604 should only be used under qualified medical supervision Baseline and monitoring laboratory testing is recommended Individual contraindications and health status must be evaluated AOD-9604 is not FDA-approved for any indication Contraindications and Precautions: Pregnancy and breastfeeding (no safety data available) Active malignancy (discuss with oncologist) Pediatric use (not studied in children) Significant organ dysfunction (limited safety data) Report Concerns: Any unexpected symptoms or adverse effects should be reported to your healthcare provider promptly