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Again, the antioxidant action of DFO in vivo may be of little importance because the blood levels reached during therapy (20 M) are too low to achieve the desired effect (Figure 11A), resulting in amplified transcription of genes promoting erythropoiesis, glycolysis, and angiogenesis (Woo et al., 2006)

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This issue is discussed in more detail in the section below on reelin and inflammation