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Moreover, suppression of the mTOR-p70S6K axis is able to induce possessing of unique metabolic features, distinguished by high glucose uptake, incremental lactate production, and low mitochondrial respiration, in TNBC cells ( Estrogen Receptor More than two-thirds of the breast cancer cases present as ER-positive, and cancers with ER-positive without HER2-positive is termed as luminal breast cancer (204)

The meeting of intestinal macrophages with commensal microorganisms under homeostatic conditions does not trigger the development of a clear inflammatory reaction, that is associated with constitutive IL-10 signaling

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Deng Y, Zou J, Hong Y, et al