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Atherosclerosis reduction by miR-30e-5p antagonism Complementary to experiments in Figure 6, we used a miR-30e-5p loss-of-function approach to test whether the exogenously delivered anti-miR-30e-5p could mitigate atherosclerosis in Apoe -/- mice (Figure 7A)

It was shown to significantly reduce symptoms of osteoarthritis such as pain and swelling

GIP has been shown to decrease appetite and increase energy expenditure, which leads to weight loss

Inhibiting ROS production may protect damaged spinal cord tissue from mitochondrial oxidative stress, neuronal apoptosis, and axon death, as high levels of ROS impair the function of blood vessels to regulate inflammation, cell proliferation, and mitochondrial autophagy