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DOI: [CrossRef] 101

Under normal physiological conditions, AEC-II is primarily responsible for producing pulmonary surfactant to maintain the surface tension and stability of alveoli [34]

Furthermore, enhanced reactive oxygen species (ROS) production after aminoglycoside treatment has been shown to promote apoptotic hair cell death via caspase-3 and nuclear factor kappa (NF-B) activation (Lee et al