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Propofol protects regulatory T cells, suppresses neurotoxic astrogliosis, and potentiates neurological recovery after ischemic stroke

Aconitum carmichaelii Debeaux (Ranunculaceae)-Chuanwu (Monograph WHO 2007), whose toxicity is reduced by 90% after processing, and possesses analgesic and anti-inflammatory effects

Disclosures KVK is a member of the speakers bureau of Axcan Pharma, manufacturer of Urso250 and Urso Forte, and gives one or two lectures a year on treatment of cholestatic liver diseases

It is generally well-tolerated, with the following side effects [9][18]: GI symptoms (most common): Nausea, vomiting, diarrhea, and abdominal discomfort, particularly at doses above 1,200 mg/day Sulfurous taste/smell: NAC has a distinct sulfur odor and taste that some find unpleasant Headache: Occasionally reported Anaphylactoid reactions (IV use only): Infusion-related reactions including flushing, itching, bronchospasm, and hypotension occur in approximately 10-20% of patients receiving IV NAC for acetaminophen overdose [18] Upper limit: There is no established UL for NAC