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KORs are also able to inhibit glutamate input to DRN 5-HT neurons (Pinnock, 1992a)

10.1016/j.cellsig.2008.08.013

For another investigational comparison, Retatrutide and Tirzepatide explains key differences

J Neuroimmunol 94:4857 Shiflett MW, Balleine BW (2010) At the limbic-motor interface: disconnection of basolateral amygdala from nucleus accumbens core and shell reveals dissociable components of incentive motivation