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Accompanied by impaired BBB integrity, these peripheral immune factors gain access to the CNS, where they mediate neuroinflammatory responses, resulting in synaptic damage and neuronal dysfunction

Springer Science Reviews 2 , 113 (2014)

184 : 11551160 Decaudin D, Geley S, Hirsch T, Castedo M, Marchetti P, Macho A, Kofler R and Kroemer G (1997) Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents