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The inward-occluded conformation, reconstructed from 149,606 particles, features an occluded substrate-binding site and a partially unwound intracellular segment of TM5 (Supplementary Fig

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On the other hand, chronic inflammation that occurs over a long period of time is associated with many diseases, including heart disease, rheumatoid arthritis, and inflammatory bowel disease ( Cruciferous vegetables like cabbage contain many different antioxidants that have been shown to reduce chronic inflammation (11)