glutathione persister cells cancer

glutathione persister cells cancer Frontiers Mechanism of Drug Tolerant Persister

Name: glutathione persister cells cancer Frontiers Mechanism of Drug Tolerant Persister
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Mechanism of Drug Tolerant Persister Cancer Cells: The Landscape and Clinical Implication for Therapy Journal of Thoracic Oncology Role of Glutathione in Cancer: From Mechanisms to Therapies Persistent Cancer Cells: The Deadly Survivors: Cell Cancer drug tolerant persister cells: from biological questions to clinical opportunities Nature Reviews Cancer

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De Knegt 7 , Dominique M Roulot 8 and Jrme Boursier 9 , (1)CHU of Angers, (2)Erasmus MC, University Medical Center, Rotterdam, Netherlands, (3)Jean Minjoz Hospital, (4)Angers University Hospital, Angers, France, (5)Laboratoire Hifih, Upres EA3859, Sfr 4208, Angers University, (6)Erasmus University Medical Center, (7)Erasmus MC, University Medical Center, (8)Avicenne Hospital, Assistance Publique- Hopitaux De Paris, (9)Service Hpato-Gastroentrologie Et Oncologie Digestive, Centre Hospitalier Universitaire, Angers, France

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To this end, various structureactivity relationship (SAR) methodologies are employed, including, but not limited to, site-directed mutagenesis, rational computational design, high-throughput screening of synthetic peptide libraries, template-guided structural refinement, and mechanism-driven design strategies inspired by natural biological processes