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Among these SAXS-based ensemble-generating approaches are the Ensemble Optimization Method (EOM) (Tria et al., 2015), the Minimal Ensemble Search (MES) (Pelikan et al., 2009), Basis-Set Supported SAXS (BSS-SAXS) (Yang et al., 2010), and the Ensemble Refinement of SAXS (EROS) (Rozycki et al., 2011)

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Lean proteins: These provide the essential amino acids glutamate and glycine