melanotic macules vulva Dermoscopic and confocal microscopy patterns of vulvar mucosal Melanocytic Nevus - Vulvovaginal Disorders

As brain-resident innate immune cells, microglia are typically the first responders to altered homeostasis within the CNS

Instead, they use different mechanisms of action which are part of the innate immune system

It remains unresolved whether reduced frataxin triggers ferroptosis by inhibiting ironsulfur cluster synthesis enzymes (such as NFS1 and ISCU) and disrupting mitochondrial iron homeostasis, nor is it known how lipid peroxidation products generated during ferroptosis further impair frataxin function and exacerbate ironsulfur cluster assembly defects

doi: 10.1002/jdn.10155 44 VelazquezRFerreiraEKnowlesSFuxCRodinAWinslowWet al