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Whereas, the food allergens translocation throughout the intestinal epithelium, during the initial phase, involves transcytosis of IgE-allergen complexes mediated by the CD23 IgE receptor in epithelial cells (157, 158)

Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial Lau DCW, Erichsen L, Francisco-Ziller N, et al

[iii] Even with careful planning and preclinical data collection, there are inherent risks and challenges associated with first-in-human clinical trials

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