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Cell lines The human breast adenocarcinoma cell line (MCF7) and the SV40-transformed human embryonic kidney 293 (HEK293T) cells were obtained from the American Type Culture Collection (ATCC) (Rockville, MD)

Silencing ATG5 did not alter the turnover of inner (OPA1) or outer (TOMM20) mitochondrial proteins, mitochondrial network (MitoTracker green), mitochondrial depolarization (TMRM), superoxide levels (MitoSOX), or the co-localization of mitochondria with the lysosomes (Supplementary Fig