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While many cases are mild, pneumococcal pneumonia can lead to severe lung infections, bloodstream infections (bacteremia), and even meningitis

doi: 10.3390/cancers14235933

Link Kapust RB, Tzsr J, Fox JD, Anderson DE, Cherry S, Copeland TD, Waugh DS

However, I/R induces injury responses including oxidative stress, excitotoxicity, inflammation, autophagy, and edema, further complicating disease progression (2125)