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other allergic reactions that have been reported include erythema, skin rash (unspecified), pruritus, general malaise, and respiratory difficulty due to bronchospasm

In the states, cyanocobalamin is the gold standard and is easily obtainable but I suspected I was getting other issues so I switched first to methyl and then hydroxocobalamin which is more easily converted to the forms the body can uptake and use

Proof-of-concept randomized controlled study of cognition effects of the proprietary extract Sceletium tortuosum (Zembrin) targeting phosphodiesterase-4 in cognitively healthy subjects: Implications for Alzheimers dementia