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Description

To determine whether overexpression of Gpx4 reduced lipid peroxidation, we also compared levels of 4-HNE adducts in spinal proteins from WT, SOD1 G93A , and SOD1 G93A GPX4 mice

The formation of prodrugs (conjugation with azo, glucuronide, cyclodextrin, dextran, or amino acids), coating with pH-sensitive polymers, coating with biodegradable polymers, timed dependent release systems, osmotic pressure-controlled systems, and redox-sensitive systems are some of the different methods for colon-targeted drug delivery [13]