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Various studies have established possible risk factors for the development of acute exacerbations, such as low FVC and DLco, and the presence of emphysema and pulmonary hypertension.42 Pulmonary Hypertension The pulmonary hypertension that appears in IPF is included within the clinical group of PH associated with interstitial lung disease (group 3) of the updated Dana Point classification, and is defined as a mean pulmonary artery pressure (PaPm) greater than 25mmHg.43 Its prevalence is estimated at 30%45% in patients evaluated for lung transplant, but it is much higher in those with longer disease evolution and at the time of transplant

The extent of UV exposure required to cause photoaging is not currently known, although the amount sufficient to cause erythema (reddening, commonly described as sunburn) in human skin is quantified as the minimal erythema dose (MED) from a given UV light source

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The list of peptides to be discussed by PCAC are listed below