Vol. XVIII · Free shipping $75+ · Read the collection
Feature · Product Review
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Genetic modification of the carotenoid pathway in the red yeast Xanthophyllomyces dendrorhous : engineering of a high-yield zeaxanthin strain

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Notably, at 6 M, curcumin synergistically reduces interleukin-1(IL-1)/IL-6 secretion by 50% through inhibition of extracellular signal-regulated kinases/c-Jun N-terminal kinases (ERK/JNK) phosphorylation (EC50 = 8.4 M) and targeting of the signal transducer and activator of transcription 3 src homology 2 (STAT3 SH2) domain (G = 7.1 kcal/mol) (Peng et al., 2021

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A.TabassamS.GulfrazM.Sheeraz AhmadM.RajaG

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doi: 10.1038/srep11722 48 CoryellPRDiekmanBOLoeserRF

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