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Cell 162 , 974986 (2015)

These intelligent systems have the ability to release their payload when certain triggers are detected in the psoriatic microenvironment, such as an increase in pH or the presence of excessively produced enzymes

In another embodiment, the method further involves obtaining a control biological sample from a control subject, contacting the control sample with a compound or agent capable of detecting the marker polypeptide, mRNA, genomic DNA, or fragment thereof, thereby detecting the presence of the marker polypeptide, mRNA, genomic DNA, or fragment thereof in the biological sample, and comparing the presence of the marker polypeptide, mRNA, genomic DNA, or fragment thereof in the control sample with the presence of the marker polypeptide, mRNA, genomic DNA, or fragment thereof in the test sample

We previously identified the receptor-like kinase PSKR1/ALR1 (ALR1) in Arabidopsis as a receptor that senses phytotoxic aluminium (Al) ions, which cause severe crop yield loss and forest decline on acidic soils widely distributed over the world