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In addition, ADCs can also exert an extracellular action on neighbouring cells via the release of the payload after intracellular cleavage of the linker (bystander effect), which is mediated by the proteases localised in lysosomes

6 State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun, Peoples Republic of China *These authors contributed equally to this work Correspondence: Tianmeng Sun

Role of glutathione-S-transferases in neurological problems

Cytosolic escape of mitochondrial DNA triggers cGAS-STING pathway-dependent neuronal PANoptosis in response to intermittent hypoxia