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For example, elevated activity of ARG1 (arginase 1) and IDO1 (indoleamine 2,3-dioxygenase 1) in aging and cancer restricts T cell function, establishing metabolic checkpoints that collectively weaken immune surveillance

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That convenience, however, creates the exact problem this article addresses when two peptides share one vial and one diluent volume, the reconstitution math governs the concentration of both simultaneously, and a single mistake in diluent volume mis-states every downstream figure for both molecules at once