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Revised: 4 nervous system surgery codes 63685 63688, 64590, and 64595 have been revised: Radiology CPT Updates New codes : 75580 for reporting a noninvasive estimate of coronary fractional flow reserve (FFR) derived from augmentative software analysis of the data set from a coronary computed tomography angiography 76984 to describe diagnostic intraoperative thoracic aorta ultrasound 76987, 76988,and 76989 : 3 new codes for epicardial ultrasound for congenital heart disease: Deleted : Pelvimetry code 74710 has been deleted

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Class Propionic acid derivative NSAID Mechanism of Action Reversibly inhibits COX-1 and COX-2 Prostaglandin synthesis pain, inflammation, fever Indications Mild to moderate pain (headache, dental pain) Dysmenorrhea Musculoskeletal pain Fever Osteoarthritis & rheumatoid arthritis Acute inflammatory conditions Dosage Adults 200400 mg every 68 hours Maximum: OTC: 1,200 mg/day Prescription: 3,200 mg/day Children 10 mg/kg per dose every 68 hours (max 40 mg/kg/day) Adverse Effects Gastrointestinal Gastritis Peptic ulcer disease GI bleeding Renal Acute kidney injury Sodium & water retention Cardiovascular Blood pressure Thrombotic risk (less than COX-2 selective NSAIDs) Others Hypersensitivity reactions Bronchospasm (aspirin-sensitive asthma) Contraindications Active peptic ulcer disease Severe renal impairment NSAID hypersensitivity 3rd trimester of pregnancy Uncontrolled heart failure Drug Interactions Anticoagulants bleeding risk ACE inhibitors / diuretics renal function Other NSAIDs toxicity Take with food to reduce GI irritation Avoid chronic use in elderly Safer than aspirin for GI bleeding, but not risk-free Avoid dehydration while using Ibuprofen = reversible COX inhibitor with good anti-inflammatory effect To view or add a comment, sign in PROTON PUMP INHIBITORS (PPIs) Definition: PPIs are drugs that irreversibly inhibit the H/K ATPase (proton pump) in gastric parietal cells, leading to suppression of gastric acid secretion