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If retatrutide is approved for multiple indications (obesity, diabetes, liver disease, osteoarthritis), coverage may be easier to obtain under non-obesity indications

But he could not totally discard Jerne's theory because, as he admitted later, Jerne's natural selection hypothesis showed a 'verve and sweep that made the self-marker ideas I was struggling with at the time look clumsy and artificial'

doi: 10.3389/fcell.2023.1127618 Received 19 December 2022 Accepted 16 February 2023 Published 27 February 2023 Volume 11 - 2023 Edited by Alessandro Luciani, University of Zurich, Switzerland Reviewed by Sean Froese, University Childrens Hospital Zurich, Switzerland Dario Brunetti, University of Milan, Italy Updates Copyright 2023 Li and Hoppe