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10.1016/j.expneurol.2020.113331 171 HashimH.AzminS.RazlanH.YahyaN

Response is highly individual, and the evidence for these specific benefits is less established than glutathione's role as an antioxidant

Furthermore, enhanced glutamine metabolism has been shown to significantly increase -KG production, which, in turn, activates the mTOR1 signaling pathway and further inhibits the autophagy-promoting kinase (APCK) of the ULK1 complex by mediating site-specific phosphorylation of ULK1 (Ser637 and Ser757) and Atg13 (Ser258) activity, thereby promoting cancer cell proliferation [27]