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154 There is increasing evidence supporting the intimate participation and pivotal regulation of the LOX AA pathway in I/R injury in enzymatic and nonenzymatic manners

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Unlike other small RNAs, tasiRNAs originate from TAS genes and require a two-step processing involving miRNA-directed cleavage and RNA dependent RNA polymerase 6 (RDR6)

Click to read the study, published today in NEJM Relevant Reading: The Interleukin-17 Pathway in Psoriasis and Psoriatic Arthritis: Disease Pathogenesis and Possibilities of Treatment In-Depth [randomized controlled trial]: This study enrolled a total of 168 patients randomized 1:1:1 into the following groups: brodalumab 140mg, brodalumab 280mg and placebo