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1 Introduction Rheumatoid arthritis (RA) is a multifactorial autoimmune disease of unknown etiology mainly characterized by synovial hyperplasia, pannus formation, as well as cartilage and bone destruction, resulting in joint pain, stiffness, and swelling

Funding This work was supported by the National Natural Science Foundation of China (No: 81872976), Health and wellness research projects of Anhui Province (No: AHWJ2022b062) and Chinese Medicine Inheritance Innovation and Development Research Project of Anhui Red Cross Society (No: 2022ZYYD06)