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Dai X, Dharmage SC, Abramson MJ, Erbas B, Bennett CM, Svanes C, Hui J, Axelrad C, Lowe AJ, Lodge CJ

Luo J, Chen YJ, Chang LJ

It was only with the availability of dioxygen did pathways evolve (Kreb Cycle, mitochondrial electron transport/oxidative phosphorylation) that allowed pyruvate to be fully oxidized to carbon dioxide, with the release of much more energy