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Unresolved inflammation results in formation of vulnerable plaques characterized by enhanced macrophage apoptosis and defective efferocytosis of apoptotic cells resulting in necrotic cell death leading to increased smooth muscle cell death, decreased extracellular matrix production, and collagen degradation by macrophage proteases

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Bacteroides vulgatus boosts nucleotide biosynthesis and DNA repair in tumor cells, enhancing resistance to 5-FU (Teng et al., 2023)

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