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Gln is the most abundant amino acid in the human body, and it not only provides essential energy and biosynthetic raw materials for tumor cells, but is also an important substance through which tumor cells maintain redox homeostasis in the tumor microenvironment

Luciferase reporter assays showed that ectopic expression of Np63, but not the transactivation defective mutant (R304W), promoted reporter activity of PHGDH-Gluc, PSAT1-Gluc, PSPH-Gluc, SLC1A4-Gluc (Fig

In the last recent years, the association between low serum levels of A1AT and the development of RA has been identified, particularly in relation to specific A1AT genotypes