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Glutamic acid decarboxylase (GAD) as a rate-limiting enzyme in glutamate/GABA cycle catalyzes the conversion of glutamate to GABA

HPLC separates the components of a sample and measures what percentage is actually the target peptide versus impurities

The analysis of cervicovaginal fluids highlighted a notable increase in the levels of IL-4 and IL-10 in women supplemented with ALA compared to placebo, while no significant changes in the levels of proinflammatory cytokines were observed between the groups

Therapeutic ketosis provides an alternative energy source when glucose is unavailable, attenuates inflammation, and reduces oxidative stress, thereby alleviating the brain energy gap without the detrimental effects of pathologic ketoacidosis or lactic acidosis [47]