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The oxidative nature of FB 1 mediates acute lipid metabolism

Similarly, peroxisome proliferator-activated receptor (PPAR)- agonists such as fenofibrate promote fatty acid oxidation, which may help clear the lipid accumulation associated with mitochondrial dysfunction and reduce inflammation-driven atherosclerosis (159)

They promote macrophage polarization to the M2 anti-inflammatory phenotype, inhibit inflammatory pathways, and may improve skin barrier function, offering theoretical benefits in RA, IBD, and psoriasis